Effects of AG 629, a new anti-ulcer agent, on experimental gastric and duodenal ulcers
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چکیده
منابع مشابه
Evaluation of Anti-ulcer Activity of Echinops Persicus on Experimental Gastric Ulcer Models in Rats
Extract of Echinops persicus is traditionally used for a long time in Iran for treatment of cough and constipation. This extract is produced by activity of bug (Situphilus spp.) on the plant. We documented its anti-tussive effect in rats in our previous study. The aim of this study was to assess the anti-ulcer effect of Echinops persicus in an animal model. In this study we evaluated anti-ulcer...
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Effects of KW-5805, a new antiulcer agent, on various experimental ulcers, necrotizing agent-induced gastric lesions and gastric acid secretion in rats were compared with those of pirenzepine and cimetidine. KW-5805 showed antiulcer activities against experimental gastric and duodenal ulcers (ED50 = 1.2-10.0 mg/kg, p.o.). KW-5805 effectively inhibited gastric lesions induced by various necrotiz...
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Introduction: Indomethacin increases generation of mitochondrial reactive oxygen species (ROS) which have a crucial role in the indomethacin-induced gastric ulcer. Coenzyme Q10 has an antioxidant activity on mitochondria and cell membranes and protects lipids from oxidation and is essential for stabilizing biological membranes. Superoxide dismutase (SOD) acts as one of the defense mechanisms ag...
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The review presents 69 references of current literature on the problem of gastroduodenal ulcer physiotherapy which has a good potential of impact on gastroduodenal motility, lipid peroxidation, microcirculation, physiological and reparative regeneration of epithelial and glandular cells. The choice of a physiotherapeutic method depends on the disease stage and to a less extent on location of th...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1982
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)54004-5